Background and Objective: Treatment adherence has an essential role in improving quality of life, survival, decreasing cost and side effects of treatment in patients underwent hemodialysis. This study aimed to determine the effect of individual multi-stage care on the treatment adherence in hemodialysis' patients, ShahrekordHajar hospital.

  Material and Methods: This clinical trial was conducted on 66 Hemodialysis patients in 2013. They were randomly allocated into two equal groups of intervention and control. The instrument was the end-stage renal disease adherence questionnaire (ESRD-AQ). The patients in intervention group were participated in 8-session individual care program for one hour in addition to routine treatment. The data was analyzed using Mann–Whitney , Wilcoxon and Spearman (P<0.05). Level.

  Results: The study indicated a significant difference between two groups in all dimensions of treatment adherence except dietary and food adherence. Adherence to treatment was better in intervention group (P<0.05). Furthermore, there was a significant correlation between adherence treatment and age of patients (P<0.05, r=0.245).

  Conclusion: based on the findings, multi-stage care is effective on different aspects of treatment adherence.